Hepatobiliary Cancers
نویسندگان
چکیده
منابع مشابه
Hereditary Pancreatic and Hepatobiliary Cancers
Hereditary etiologies of pancreatic and hepatobiliary cancers are increasingly recognized. An estimated >10% of pancreatic and increasing number of hepatobiliary cancers are hereditary. The cumulative risk of hereditary pancreatic cancer ranges from measurable but negligible in cystic fibrosis to a sobering 70% in cases of hereditary pancreatitis. Candidates for pancreatic cancer surveillance a...
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MicroRNAs (miRNAs) are small non-coding RNAs that function as endogenous silencers of numerous target genes. Hundreds of miRNAs have been identified in the human genome. miRNAs are expressed in a tissue-specific manner and play important roles in cell proliferation, apoptosis, and differentiation. Aberrant expression of miRNAs may also contribute to the development and progression of human hepa...
متن کاملSymptom concerns and quality of life in hepatobiliary cancers.
PURPOSE/OBJECTIVES To describe the symptom concerns of patients with hepatocellular carcinoma (HCC) and pancreatic cancer and explore the effect of symptoms on patients' quality of life (QOL). DESIGN Descriptive, longitudinal study. SETTING Ambulatory clinics of a comprehensive cancer center. SAMPLE 45 patients actively receiving treatment for either HCC or pancreatic cancer. METHODS Pa...
متن کاملCancer vaccines and immunotherapeutic approaches in hepatobiliary and pancreatic cancers
Hepatobiliary and pancreatic cancers along with other gastrointestinal malignancies remain the leading cause of cancer-related deaths worldwide. Strategies developed in the recent years on immunotherapy and cancer vaccines in the setting of primary liver cancer as well as in pancreatic cancer are the scope of this review. Significance of orthotopic and autochthonous animal models which mimic an...
متن کاملWnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers
OBJECTIVE Transcribed-ultraconserved regions (T-UCR) are long non-coding RNAs which are conserved across species and are involved in carcinogenesis. We studied T-UCRs downstream of the Wnt/β-catenin pathway in liver cancer. DESIGN Hypomorphic Apc mice (Apcfl/fl) and thiocetamide (TAA)-treated rats developed Wnt/β-catenin dependent hepatocarcinoma (HCC) and cholangiocarcinoma (CCA), respective...
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ژورنال
عنوان ژورنال: Journal of the National Comprehensive Cancer Network
سال: 2009
ISSN: 1540-1405,1540-1413
DOI: 10.6004/jnccn.2009.0027